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Publications

Sokol, H ; Pigneur, B ; Watterlot, L ; Lakhdari, O ; Bermúdez-Humarán, LG ; Gratadoux, JJ & al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2015, 105:16731-6

Sokol, H ; Seksik, P ; Furet, JP ; Firmesse, O ; Nion-Larmurier, I ; Beaugerie, L & al. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis, 2009, 15:1183-9

Martín, R ; Chain, F ; Miquel, S ; Lu, J ; Gratadoux, JJ ; Sokol, H & al. The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis 2014, 20:417-30

Sarrabayrouse, G ; Bossard, C ; Chauvin, JM ; Jarry, A ; Meurette, G ; Quévrain, E & al. CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. PLoS Biol 2014, 12:e1001833

Martín, R ; Miquel, S ; Chain, F ; Natividad, JM ; Jury, J ; Lu, J & al. Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model. BMC Microbiol,2015,15:67

Miquel, S ; Leclerc, M ; Martin, R ; Chain, F ; Lenoir, M ; Raguideau, S & al. Identification of metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii. mBio, 2015, 6

Miquel, S ; Martín, R ; Lashermes, A ; Gillet, M ; Meleine, M ; Gelot, A & al. Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models.. Sci Rep 2016, 6:19399

Rossi, O ; van Berkel, LA ; Chain, F ; Tanweer Khan, M ; Taverne, N ; Sokol, H & al. Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses. Sci Rep, 2018, 6:18507

Quévrain, E ; Maubert, MA ; Michon, C ; Chain, F ; Marquant, R ; Tailhades, J & al. Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn''s disease. Gut 2016, 65:415-425

Lamas, B ; Richard, ML ; Leducq, V ; Pham, HP ; Michel, ML ; Da Costa, G & al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands.. Nat Med 2016, 22:598-605

Sokol, H ; Leducq, V ; Aschard, H ; Pham, HP ; Jegou, S ; Landman, C & al. Fungal microbiota dysbiosis in IBD.. Gut 2017, 66: 1039-1048

Agus, A ; Planchais, J ; Sokol, H. Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease. Cell Host Microbe 2018, 23: 716-724

Godefroy, E ; Alameddine, J ; Montassier, E ; Mathé, J ; Desfrançois-Noël, J ; Marec, N & al  T-Regulatory Cells, Which Are Decreased in Blood Samples From Patients With Inflammatory Bowel Diseases. Gastroenterology 2018, 155: 1205-1217

Natividad, JM ; Agus, A ; Planchais, J ; Lamas, B ; Jarry, AC ; Martin, R & al. Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.. Cell Metab 2018, 28: 737-749.e4

Miani, M ; Le Naour, J ; Waeckel-Enée, E ; Verma, SC ; Straube, M ; Emond, P & al. Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes. Cell Metab, 2018, 28: 557-572.e6

Laurans, L ; Venteclef, N ; Haddad, Y ; Chajadine, M ; Alzaid, F ; Metghalchi, S & al. Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. Nat Med, 2018: 24: 1113-1120

Alameddine, J ; Godefroy, E ; Papargyris, L ; Sarrabayrouse, G ; Tabiasco, J ; Bridonneau, C & al. Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction. Front Immunol 2019, 10:143

Aschard, H ; Laville, V ; Tchetgen, ET ; Knights, D ; Imhann, F ; Seksik, P & al. Genetic effects on the commensal microbiota in inflammatory bowel disease patients. PLoS Genet 2019, 15: e1008018

Lenoir, M ; Martín, R ; Torres-Maravilla, E ; Chadi, S ; González-Dávila, P ; Sokol, H & al. Butyrate mediates anti-inflammatory effects of  Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3. Gut Microbes 2020, 12:1-16

Sokol, H ; Landman, C ; Seksik, P ; Berard, L ; Montil, M ; Nion-Larmurier, I & al. Fecal microbiota transplantation to maintain remission in Crohn''s disease: a pilot randomized controlled study. Microbiome 2020, 8:12

Lamas, B ; Hernandez-Galan, L ; Galipeau, HJ ; Constante, M ; Clarizio, A ; Jury, J & al. Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation. Sci Transl Med 2020, 12

Agus, A ; Clément, K ; Sokol, H. Gut microbiota-derived metabolites as central regulators in metabolic disorders. Gut 2020

Sokol, H ; Brot, L ; Stefanescu, C ; Auzolle, C ; Barnich, N ; Buisson, A & al. Prominence of ileal mucosa-associated microbiota to predict postoperative endoscopic recurrence in Crohn''s disease. Gut 2020, 69: 462-472

Lemoinne, S ; Kemgang, A ; Ben Belkacem, K ; Straube, M ; Jegou, S ; Corpechot, C & al. Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis. Gut 2020, 69: 92-102

Michaudel, C ; Sokol, H  The Gut Microbiota at the Service of Immunometabolism. Cell Metab. 2020, 32: 514-523

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